Pipeline & Research
Pipeline & Research
Oncology Pipeline
Oncology research at Bayer prioritizes cutting-edge science across a range of areas of research. Our current research is focused on 3 key areas: Tumor intrinsic pathways, next-generation immuno-oncology, and targeted radionuclide therapies.
The compounds presented are investigational or are being investigated for uses that have not been approved by the US Food and Drug Administration (FDA), European Medicines Agency (EMA), or other health authorities. This information is presented only for purposes of providing a general overview of clinical trials and should not be construed as a recommendation for use of any product for unapproved uses.
Tumor Intrinsic Pathways - Androgen Receptor Signaling
Androgen receptor signaling occurs through the binding of androgens or alternative ligands to the receptor, which causes translocation of the receptor complex to the nucleus.
Tumor Intrinsic Pathways - HER2/mEGFR Inhibitor
Human epidermal growth factor receptor 2 (HER2) and mutant epidermal growth factor receptor (mEGFR) are proteins that help cells to grow and divide.
Immuno-oncology
Anti-tumor immune response can be enhanced by targeting different immune-mediated pathways.
Tumor Intrinsic Pathways -Oncogenic Signaling
Activation of many oncogenic signaling pathways due to genetic alterations and/or driver mutations plays a critical role in cancer development. Dysregulation of these oncogenic pathways may promote cancer progression through changes in various cellular events.
Targeted Radionuclide Therapy
Alpha particles are believed to cause complex DNA double-strand breaks in cancer cells and the tumor microenvironment, potentially leading to cell death.
Compounds in Oncology Clinical Development Brochure
Explore our expanding commitment to clinical research and patients. The ongoing clinical trials Iisted in this brochure represent a comprehensive overview of Bayer's clinical pipeline in Oncology, including Bayer-sponsored research and collaborative research with academic centers, cooperative groups, and other global institutions.
Compounds in Oncology Clinical Development Brochure
Explore our expanding commitment to clinical research and patients. The ongoing clinical trials Iisted in this brochure represent a comprehensive overview of Bayer's clinical pipeline in Oncology, including Bayer-sponsored research and collaborative research with academic centers, cooperative groups, and other global institutions.
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